Shanna Isaacson in the Cast Courts

Dr Shanna Isaacson

Research Grants Manager

I joined the V&A in 2022 from Great Ormond Street Hospital Charity where, as Grants Manager, I led the development and implementation of strategies within its priority areas of research, data and digital, patient and family experience, and support for hospital staff. Prior to that I worked at Wellcome, where I developed and managed large strategic initiatives across the Genetics & Molecular Sciences funding portfolio including a quinquennial review of the Wellcome Sanger Institute. I was also a member of a public engagement funding committee and managed the inaugural competition of the Hub Award based in Wellcome Collection.

I have a PhD in Biophysical Chemistry from the University of Cambridge; in this I used innovative mass spectrometry to study interactions between proteins in molecular ‘machines’.

Publications

Guffick, C., Hsieh, P.Y., Ali, A., Shi, W., Howard, J., Chinthapalli, D.K., Kong, A.C., Salaa, I., Crouch, L.I., Ansbro, M.R., Isaacson, S.C. … & Van Veen, H. W., ‘Drug‐dependent inhibition of nucleotide hydrolysis in the heterodimeric ABC multidrug transporter PatAB from Streptococcus pneumoniae’, The FEBS Journal, 289 (13), July 2022, pp. 3770–3788

Zhou, M., Morgner, N., Barrera, N.P., Politis, A., Isaacson, S.C., Matak-Vinković, D., Murata, T., Bernal, R.A., Stock, D. and Robinson, C.V., ‘Mass spectrometry of intact V-type ATPases reveals bound lipids and the effects of nucleotide binding’, Science, 334(6054), 21 October 2011, pp. 380–385

Barrera, N.P., Isaacson, S.C., Zhou, M., Bavro, V.N., Welch, A., Schaedler, T.A., Seeger, M.A., Miguel, R.N., Korkhov, V.M., Van Veen, H.W., Venter, H., Walmsley A.R., Tate C.G., Robinson C.V., ‘Mass spectrometry of membrane transporters reveals subunit stoichiometry and interactions’, Nature methods, 6 (8), 2009, pp. 585–587

Opportunities

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